QuickView for g substrate;jsessionid=A24E1603FF449D706259857C41013EDF;jsessionid=F0D82A256D51BB9D322D12BD01D99AA1 (gene)

Gene Symbol:

PPP1R17 Homo sapiens

Full name:

protein phosphatase 1 regulatory subunit 17

Synonyms:

C7orf16, GSBS, protein phosphatase 1 regulatory subunit 17, G-substrate

Genomic Location:

Chr 7: 31693372-31714594

Description:

The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoform...

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The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCANCTGNY_MYOD_Q6 ,  GATAAGR_GATA_C ,  RYTGCNWTGGNR_UNKNOWN ,  RFX1_02 ,  E47_01 ,  AP4_Q6_01 ,  CAGCTG_AP4_Q5 ,  AACTTT_UNKNOWN ,  AP4_Q5 ,  GTTRYCATRR_UNKNOWN

Cytogenetic Map:

7p14.3

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